Posts Tagged ‘probiotic’

Oral Probiotics: Natural Remedy for Cold and Flu?

Q: Is BLIS K12 Probiotic Gum a natural remedy for the common cold and flu?

Professor John Tagg’s Answer:

Is BLIS K12 Probiotic Gum a natural remedy for cold and flu?The short answer is “yes.”

Awareness of the potential for anti-viral activity associated with the use of K12 preparations first came from some customer’s reports that heavy dosing with the product at the very first (prodromal) signs of an upper respiratory tract infection appeared sometimes to interfere with the customary clinical progression of their infection.

The interferons are cytokines that help trigger various protective defences of the immune system and some of these are especially important for fighting off virus infections. We found that (a)  the exposure of preparations of either mouse splenocytes or human leukocytes to K12 cells and (b) the consumption of large numbers of K12 cells by human subjects resulted in production of substantially elevated levels of gamma interferon. In other studies it has been shown that protection of the human host against virus infection can be triggered by gamma interferon (1) .

More recently (2)  K12 cells were shown to suppress bronchial and other epithelial cell inflammatory responses by inhibiting NF-kB pathways and other important immune cell functions.

My recommendation for those attempting to alleviate the progression of a viral upper respiratory tract infection is as follows –  at the very first signs of infection successively use 3 K12 chewing gums over a period of 10 -15 min and then repeat this another one or two times over the next two hours.

References:

1.  Sethi S.K., Bianco, A., Allen, J.T., Knight, R.A., Spiteri, M.A. Interferon-gamma (IFN-gamma) down-regulates the rhinovirus-induced expression of intercellular adhesion molecule-1 (ICAM-1) on human airway epithelial cells.Clin Exp Immunol 110: 362-9 (1997

2. Cosseau C., Devine D.A., Dullaghan E., Gardy J.L., Chikatamarla A., Gellatly S., Yu L.L., Pistolic J., Falsafi R., Tagg J., Hancock R.E. The commensal Streptococcus salivarius K12   downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis. Inf. Immun 76: 4163-75 (2008)

(Do you have a Probiotic Health question for Professor John Tagg? Email us your question. If your question is not listed in our FAQ’s, we’ll ask Professor Tagg directly, email you back with his answer, AND post it here on our blog to benefit all our readers.)

“Probiotic Professor” John Tagg to Visit BC Health Food Stores and Appear on TV

Professor John TaggProfessor John Tagg, “The Probiotic Professor” will be in Vancouver as a guest speaker at the Canadian Health Food Association‘s annual Expo West industry convention and trade show this month.

Professor Tagg will also be visiting select health food stores in the Vancouver/Victoria region… PLUS he’ll be appearing on Fanny Kiefer’s TV show “Studio 4″ talking about his discovery of the oral probiotic BLIS K12.

(We’ll be giving away free samples of our CulturedCare Probiotic Gum w/ BLIS K12 at Professor Tagg’s health food store events.)

Professor John Tagg’s May, 2010 Vancouver  itinerary:

Thursday, May 13 – TV appearance on Fanny Kiefer’s Studio 4 (Shaw TV)
Broadcast Live at 9:00 am PST (and again at 1, 4 and 9pm PST)

Monday, May 17 – Instore at Whole Foods / Capers – Cambie
12-1pm
510 W. 8th Ave (at Cambie)
Vancouver BC
778-370-4217

Monday, May 17 – Instore at Nature’s Fare Markets-Langley

2-4 pm
#120-19880 Langley Bypass
Langley BC V3A 4Y7
Phone Number 788-278-1300

Tuesday, May 18 – Instore at The Vitamin Shop
1-3 pm
1212 Broad St.
Victoria BC V8W 2A5

Wednesday, May 19 – Instore at Lifestyle Markets
1-2 pm
180-2950 Douglas St. Victoria BC

Wednesday, May 19 – Instore at Lifestyle Select
2:30-3:30 pm
9769 5th St.
Sidney BC

Ask Professor Tagg – “BLIS K12 Probiotic Gum for Sjogren’s Syndrome?”

(Do you have a Probiotic Health question for Professor John Tagg? Email us your question. If your question is not listed in our FAQ’s, we’ll ask Professor Tagg directly, email you back with his answer, AND post it here on our blog to benefit all our readers.)

Reader’s Question:

What about this gum for persons with Sjogren’s Syndrome? It’s an autoimmune disease which damages the moisture producing glands including the salivary glands. Excessive bacteria is a problem for persons with Sjogren’s due to lack of saliva. Thrush and oral yeast infections are regular issues. How would your gum work for that?

Professor John Tagg’s Answer:

Indeed the Probiotic Gum is perfectly applicable to individuals experiencing the hyposalivation of Sjogren’s Syndrome. The chewing of the gum not only will help stimulate saliva production but the release of BLIS K12 and subsequent colonisation will help counter oral thrush as the K12 cells occupy space on the mucosal surfaces that otherwise is vulnerable to fungal infiltration.

“BLIS K12 fights Bad Breath” VIDEO w/ Professor John Tagg

In this video, Professor John Tagg from Otago University talks briefly about how probiotic S. salivarius BLIS K12 fights the bacteria that cause bad breath.

How Can You Colonize Healthy Probiotic Bacteria in Your Mouth?

We’ve all heard that “Digestion starts in the mouth.” But probiotic supplements like acidophilus have typically targeted only the lower intestinal tract. BLIS K12 is different. It is a probiotic for the mouth. It doesn’t pass through the stomach and live in the lower intestine like other probiotics. It stays in the mouth, colonizing on your tongue and protecting against infection where it most often enters the body… through the mouth and nose.

So how can you colonize friendly BLIS K12 probiotic bacteria in your mouth and start benefiting from the “infection protection” it provides? In this video, Professor John Tagg gives the short answer to this question, while pointing out that the mouth is actually the beginning or “front” of the intestinal tract, with its own unique flora.

We Got Science. 40+ links to scientific studies… at your fingertips.

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We’re getting a lot of excitement and questions from the natural health communities as we near launch date with our new CulturedCare Probiotic Gum with BLIS K12. People recognize that this product represents an exciting new chapter in Probiotics… and an absolute FIRST for health-minded Canadian consumers.

One of the questions that we appreciate is “Where can I learn more about the research and science behind probiotic BLIS K12?”

Professor John Tagg has been studying this unique probiotic for over 30 years. If you’re interested in learning about his research and you want to review published scientific articles by him and his colleagues, a great place to start is here:
http://www.springerlink.com/content/dg56pk5k48l6w5h1/fulltext.html

The above link will take you to an article “overview” by Professor Tagg that is accessible enough for most people, with enough technical meat to satisfy scientific types. At the end of the article is a useful list of over 40 relevant scientific articles by Professor Tagg and his colleagues. Most of the article titles are followed by a link to PubMed, an online database of published scientific articles.

You can also find links to selected articles in our own reference section here:
http://culturedcare.com/references/

At CulturedCare we work collaboratively with Professor John Tagg and the BLIS K12 team. If you have a request for a specific published article, please let us know and we will do our best to get it for you.

BLIS K12 – “Hundreds of times more effective than even most traditional antiseptic throat lozenges”

BLIS K12 is the world’s only probiotic specifically designed to protect the entire oral cavity which includes the throat, mouth, gums and teeth. Under specific conditions, it has even been shown to protect the nasal sinus from infection.   BLIS K12 is known as an advanced probiotic, because unlike other probiotic organisms, it will produce antibacterial peptides (called BLIS) when it is under threat from a potential disease-causing bacteria. Studies on the potency of the antibacterial effect of the advanced probiotic organism demonstrates that it is hundreds of times more effective than even most traditional antiseptic throat lozenges if used as an oral antiseptic.
Jocelyn Mathern, (M.S., R.D.), Technical Health Manager for Frutarom, reported that a research group from the University of British Columbia, Vancouver, Canada, recently published a paper on the unique properties of the organism BLIS K12, in the scientific journal from the American Society of Microbiology,  called “Infection and Immunity”. The research paper went beyond examining the classic probiotic activity of certain bacteria to determine if the BLIS K12 probiotic conferred any additional benefit, simply by colonizing in the oral cavity.
“What’s exciting about this research is that it showed that BLIS K12 exhibited a pronounced anti-inflammatory effect and this was directly related to its interaction and colonization with its host (i.e. the person taking it). This demonstrates that the human body actually responds in positive and beneficial ways, in the presence of BLIS K12, unlike many of the other bacteria that can be found within the human body.”  Mathern said.  “Additionally the study also suggested that the BLIS K12 could switch on the genes in the epithelial tissue that are responsible for cellular rebuilding and repair, especially after a cell has been damaged by a pathogen.”
The research group that investigated BLIS K12 took several months to complete their work and involved researchers from the University of British Columbia (Canada), University of Leeds (UK), Inimex Pharmaceuticals (Canada), and the University of Otago (New Zealand). They now confirm that the beneficial effects of the probiotic BLIS K12 goes  beyond the unique ability to produce its well-known, anti-bacterial peptides  (called BLIS), which are clinically demonstrated  to kill bacteria implicated in upper airways infection, chronic bad breath and bacterial infections of the oral cavity.  “We know that BLIS K12 has protective benefits against sore throats and upper respiratory infections, but this research suggests that if you are already sick, BLIS K12 can stimulate an immune response to help a person recover faster,” stated Mathern.
Just prior to this publication from the group at the University of British Columbia, another important study appeared in the European Journal of Clinical Microbiology & Infectious Diseases.  In this earlier study it was suggested that the advanced probiotic, BLIS K12, could exert a long term protective effect upon the upper respiratory tract (ear, nose and throat) if the subjects sucked on a series of BLIS K12 lozenges immediately after a course of antibiotics. The study suggested that BLIS K12 had the potential for unique application of protection against ear infections in children.
INFECTION AND IMMUNITY,      Sept. 2008, p. 4163–4175 Vol. 76, No. 9
DR. M. ROHDE, HELMHOLTZ CENTRE FOR INFECTION RESEARCH,  Braunschweig, Germany
MICROBE Oct 2008, Commentary on Infect. Immun. 76:4163–4175
EUR J CLIN MICROBIOL INFECT DIS,    DOI 10.1007/S10096-008-0569-4
BLIS K12

BLIS K12

BLIS K12 is the world’s only probiotic specifically designed to protect the entire oral cavity which includes the throat, mouth, gums and teeth. Under specific conditions, it has even been shown to protect the nasal sinus from infection.   BLIS K12 is known as an advanced probiotic, because unlike other probiotic organisms, it will produce antibacterial peptides (called BLIS) when it is under threat from a potential disease-causing bacteria. Studies on the potency of the antibacterial effect of the advanced probiotic organism demonstrates that it is hundreds of times more effective than even most traditional antiseptic throat lozenges if used as an oral antiseptic.

Jocelyn Mathern, (M.S., R.D.), Technical Health Manager for Frutarom, reported that a research group from the University of British Columbia, Vancouver, Canada, recently published a paper on the unique properties of the organism BLIS K12, in the scientific journal from the American Society of Microbiology,  called “Infection and Immunity”. The research paper went beyond examining the classic probiotic activity of certain bacteria to determine if the BLIS K12 probiotic conferred any additional benefit, simply by colonizing in the oral cavity.

“What’s exciting about this research is that it showed that BLIS K12 exhibited a pronounced anti-inflammatory effect and this was directly related to its interaction and colonization with its host (i.e. the person taking it). This demonstrates that the human body actually responds in positive and beneficial ways, in the presence of BLIS K12, unlike many of the other bacteria that can be found within the human body.”  Mathern said.  “Additionally the study also suggested that the BLIS K12 could switch on the genes in the epithelial tissue that are responsible for cellular rebuilding and repair, especially after a cell has been damaged by a pathogen.”

The research group that investigated BLIS K12 took several months to complete their work and involved researchers from the University of British Columbia (Canada), University of Leeds (UK), Inimex Pharmaceuticals (Canada), and the University of Otago (New Zealand). They now confirm that the beneficial effects of the probiotic BLIS K12 goes  beyond the unique ability to produce its well-known, anti-bacterial peptides  (called BLIS), which are clinically demonstrated  to kill bacteria implicated in upper airways infection, chronic bad breath and bacterial infections of the oral cavity.  “We know that BLIS K12 has protective benefits against sore throats and upper respiratory infections, but this research suggests that if you are already sick, BLIS K12 can stimulate an immune response to help a person recover faster,” stated Mathern.

Just prior to this publication from the group at the University of British Columbia, another important study appeared in the European Journal of Clinical Microbiology & Infectious Diseases.  In this earlier study it was suggested that the advanced probiotic, BLIS K12, could exert a long term protective effect upon the upper respiratory tract (ear, nose and throat) if the subjects sucked on a series of BLIS K12 lozenges immediately after a course of antibiotics. The study suggested that BLIS K12 had the potential for unique application of protection against ear infections in children.

INFECTION AND IMMUNITY,      Sept. 2008, p. 4163–4175 Vol. 76, No. 9

DR. M. ROHDE, HELMHOLTZ CENTRE FOR INFECTION RESEARCH,  Braunschweig, Germany

MICROBE Oct 2008, Commentary on Infect. Immun. 76:4163–4175

EUR J CLIN MICROBIOL INFECT DIS,    DOI 10.1007/S10096-008-0569-4

(Full article at http://www.npicenter.com/anm/templates/newsATemp.aspx?articleid=22916&zoneid=8)

Probiotics For Your Mouth – John Tagg, Strep and the BLIS K12 story (part 1) Video

When I first met Professor Tagg and heard his personal story about Strep
throat and his ultimate discovery of BLIS K12, a natural probiotic to
prevent it, I knew it was something that needed to be shared. Here is the
first video in a forthcoming series of short video interviews with Professor
Tagg, one of the world’s foremost Streptococcus researchers.

When I first met Professor Tagg and heard his personal story about Strep throat and his ultimate discovery of BLIS K12 (a natural probiotic to prevent it) I knew it was something that needed to be shared. Here is the first video in a forthcoming series of short video interviews with Professor Tagg, one of the world’s foremost Streptococcus researchers.

(Please be patient if the video takes some time to load. YouTube can be slow.)